Chapter 2: Translating the Evidence: Patient Cases

Case 1:

A 47-year-old man referred for evaluation of obesity, type 2 diabetes and dyspnea on exertion.  After talking to him, you make some important notes about his medical history (shown below):

  • HS graduation weight: 162 lb., BMI – 23.2 kg/m2
  • Active during college but then took a sedentary job, began eating excessively, was less active and gained ~40 lb. over 15 years.
  • T2DM diagnosed at age 42 when weight was 232 lb., BMI 33.3 kg/m2
  • Developed left arm pain while bowling 2 years ago and had a PCI + drug-eluting stent.
  • Hypertensive since college but untreated until his PCI.
  • Multiple self-prescribed lifestyle attempts at weight loss have failed and he’s not sought help.
  • Family history + for T2DM but only late onset ASCVD.
  • Over the past 2-3 weeks he has noticed some dyspnea while walking the dog.
  • Works a sedentary job as a computer analyst.
  • No tobacco, 3 beers on weekends.
  • Diet – 2 servings of fruits and vegetables & 1 serving of whole grains daily, fish once weekly. Doesn’t read food labels and watches CHO intake but not sodium.
  • Exercise – walks the dog ~15 min twice daily.

Current Medications

Lisinopril 40 mg daily
Aspirin 81 mg daily
Atorvastatin 40 mg daily
Metformin 1700 mg AM, 850 mg PM
Sitagliptin 100 mg daily
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